Source Naturals CALCIUM D-GLUCARATE includes the patented compound glucarate which has been shown in animal studies to support major detoxification pathways in the body. Calcium d-glucarate, the calcium salt of d-glucaric acid, is found naturally in the human body and in a variety of fruits and vegetables. Animal studies have shown that high doses of calcium d-glucarate may modulate beta-glucuronidase, and thereby support the process of glucuronidation. Glucuronidation is one of the body’s healthy processes in which foreign organic compounds, fat-soluble toxins and excess steroid hormones such as estrogen are detoxified and excreted.*