Active B6

Pyridoxal-5-Phosphate (P5P) is the metabolically active form of vitamin B6 found in the body, and is known to be necessary for the transformation and utilisation of amino acids for many functions in the body, including energy production and neurotransmitter synthesis.

Activated B6 plays a crucial role in supporting the Methylation and Transulfation pathways and is involved in the production of hemoglobin, Intrinsic Factor, and is a vital component in the formation of the Myelin sheath that surrounds nerve cells

Metabolically Active Form
For vitamin B6 to be utilised by the body, it must first be converted to P5P in the liver. Individuals with compromised liver function may not be able to efficiently make this conversion, and consequently may be at risk of a vitamin B6 deficiency. Out of 31 patients with impaired liver function, 22 had significantly lower plasma P5P levels than normal. Supplementing with RN Labs Active B6 ensures patients receive the most bioactive form of vitamin B6.

Schaumburg, H, Kaplan, J, Windebank, A, Vick, N, Rasmus, S, Pleasure, D & Brown, MJ 1983, ‘Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome’, The New England Journal of Medicine, vol. 309, pp. 445-8.
Labadarios, D, Rossouw, JE, McConnell, JB, Davis, M & Williams, R 1977, ‘Vitamin B6 deficiency in chronic liver disease – evidence for increased degradation of pyridoxal-5-phosphate’, Gut, vol. 18, pp. 23-7.